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Last name origin & meaning:

Spanish: from the personal name Diego, which is of uncertain derivation. It was early taken to be a reduced form of Santiago, and is commonly taken by English speakers as being a form of James, but this is no more than folk etymology. It is found in the Middle Ages in the Latin forms Didacus and Didagus, which Meyer-Lübke derived from Greek didakhē ‘doctrine’, ‘teaching’, but in view of the fact that it is unknown outside the Iberian Peninsula it may possibly have a pre-Roman origin.

This name appears in the following lists: Cartoon Characters, Cities